Ubiquinol May Improve Mitochondrial Dysfunction

Ubiquinol may improve function in people with mitochondrial dysfunction, according to a new Dutch study.i

The breakthrough study found that mitochondrial dysfunction can be partially reversed using Ubiquinol – the active and the major form of CoQ10 that naturally occurs in the body.

Up to one in 200 Australians are at risk of developing Mitochondrial Diseases, a group of chronic illness that robs sufferers of energy, and damages the muscles and major organs like the brain and stomach. One Australian child born each week will develop a severe or life-threatening form of mitochondrial disease.i

Mitochondria are known as the ‘powerhouse’ of cells and act like a digestive system that takes in nutrients, breaks them down, and creates energy for the cell.

CoQ10 is often used as a therapy for mitochondrial disorders to increase energy production and help reduce toxic by-products that may be associated with these disorders.

People who have mitochondrial diseases are often deficient in Coenzyme Q10 but many people with these diseases cannot effectively absorb standard CoQ10 supplements.

CoQ10 has been reported to have a beneficial effect on symptoms and overall outcome in a number of mitochondrial disorders.iii,iv,v,vi

The double-blinded, placebo-controlled study medically-induced a state of mitochondrial dysfunction. Half of the 28 participants were given Ubiquinol and the other half placebo. After eight weeks, participants who were given Ubiquinol returned to their original mitochondrial function, while the placebo group still had significantly impaired mitochondrial function.

Principal of Health Schools Australia, Stephen Eddey, said the study found conventional CoQ10 may be poorly absorbed and may not be as easily used in patients with mitochondrial disease.
The study also found Ubiquinol was also more effective than conventional Coenzyme Q10 in reducing some of the damaging processes of mitochondrial diseases including oxidative damage in the brain.

“The study suggests that Ubiquinol may improve the results of CoQ10 supplementation in people with deficiencies, other mitochondrial diseases and neurodegenerative diseases,” Eddey said.

About Ubiquinol
Ubiquinol is the purest, or synthesized, form of CoQ10. Produced naturally within the body, Ubiquinol is CoQ10 that has been reduced to make it more readily usable by the body.
It is also one of the most powerful known fat-soluble antioxidants available.
This helps it protect the body’s cells from damage caused by oxidative stress and free radicals.
It also has a superior absorption ability which means you can take a lower dose for the same effect.
There are many national brands that make products that contain Ubiquinol. Ask your health practitioner or local pharmacist for the best product for you.

Ubiquinol Benefits:
• Strong antioxidant – helps soak up oxidative stress and free radicals
• Support the heart – helps maintain a healthy heart and vascular system
• Cholesterol Support – helps maintain healthy LDL cholesterol levels in healthy people
• More easily absorbed into the body compared to standard CoQ10
• Powers Your Cells – helps your body’s cells convert energy

Consult your healthcare practitioner on strategies for your health.
Always read the label. If symptoms persist consult your healthcare practitioner.

For more information visit www.kanekaqh.info/

i Novel In Vivo Human Model For Transient Mitochondrial Dysfunction: Simvastatin-Induced Mitochondrial Dysfunction In Healthy Subjects And Its Reversibility By The Reduced Form Of Co-Enzyme Q10. Journal of World Mitochondria Society 2015 (2015) http://journal.medsys-site.com/WMS/article/view/322
ii Mitochondrial Disease Fact Sheet – http://www.amdf.org.au/wp-content/uploads/2014/05/Mitochondrial-Disease-Fact-Sheet.pdf
iii Chan A, Reichmann H, Kogel A, Beck A, Gold R. Metabolic changes in patients with mitochondrial myopathies and effects of coenzyme Q10 therapy. J Neurol. 1998;245:681-685.
iv Chen RS, Huang CC, Chu NS. Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study. Eur Neurol. 1997;37:212-218.
v Bresolin N, Doriguzzi C, Ponzetto C, et al. Ubidecarenone in the treatment of mitochondrial myopathies: a multi-center double-blind trial. J Neurol Sci. 1990;100:70-78.
vi Glover EI, Martin J, Maher A, Thornhill RE, Moran GR, Tarnopolsky MA. A randomized trial of coenzyme Q10 in mitochondrial disorders.Muscle Nerve. 2010;42(5):739-748.