The Best HRT Outcomes Start With The Best Ingredients

As awareness of hormone-related problems has grown, so has the mass production of medications to treat them. But each person’s body is different, and commercially manufactured products, which tend to be “one-size-fits-all,” don’t always account for that.

Not only was PCCA the first supplier to provide hormone replacement therapy products for compounding, we also back them up with studies and continue to innovate new solutions to help your patients feel like themselves again.

No two women are alike, of course, and compounding pharmacists understand this fact.

Pharmacy compounding is the art and science of preparing customised medications for patients. The advantage of compounded HRT is that it can be adapted specifically to fit each individual’s body and hormone levels. HRT can utilise hormones that have the exact chemical structure as the hormones in the human body. The body recognises them and allows them to mimic the function of the hormones the body produces on its own.

A compounding pharmacist can provide a hormone evaluation for the patient to fill out. A pharmacist experienced in HRT may assist the healthcare provider in helping interpret the results of serum of saliva tests which measure a patient’s hormone levels. The healthcare provider, compounding pharmacist, and the patient can use the results of these diagnostic tools to help determine a course of treatment which will give the patient the exact amount of hormones her body needs.

Working closely with a woman and her healthcare provider, a compounding pharmacist can help a woman start and maintain a hormone replacement regimen that brings her hormones back into balance and closely mimics what her body has been doing naturally for years. With a healthcare provider’s prescription, the pharmacist can prepare hormones in a variety of strengths and dosage forms.

Once the therapy has begun, the pharmacist will continue to work with the woman and her prescriber to make sure the HRT is working correctly, adjusting the dosage if necessary to ensure that the medication is just right for her body.

The advantage of compounded HRT is that the dose can be adjusted to fit a person’s specific needs and hormone levels. Topical administration is often a good choice for HRT, but it’s important to use a base that is proven to deliver the hormones through the skin effectively.

 VersaBase^®

Cream: PCCA #30-3641 | Gel: PCCA #30-3656

Exclusively available to PCCA members, VersaBase is the most used base for vaginal and topical hormone preparations.

The cream form is gentle, yet stable and durable, simulating the natural moisturising barrier of the skin through its emulsion system to deliver the ideal release profile for APIs like progesterone. Formulated without oil, parabens, propylene glycol, petrochemicals or petrolatum, VersaBase is odour-free and spreads easily and absorbs quickly.

VersaBase’s gel form is transparent, smooth and light to touch, with a silky feel that spreads and absorbs easily. It is extremely stable, is formulated without surfactant emulsifiers, and can be used topically, vaginally and on mucous membranes. It can be used as a thickener or stabiliser for oil-in-water emulsions, to easily create hydroalcoholic gels for hormone replacement therapy in men, or to make surfactant-free “gel-creams”.

Both VersaBase Cream and Gel are:

• Stable – Can be formulated with a variety of APIs at a wide pH range.
• Versatile – Can be used topically or vaginally; the gel can also be used on mucous membranes.

Special Micronised Progesterone

PCCA #30-3530

PCCA’s Special Micronised Progesterone not only meets USP standards, it exceeds them when it comes to particle size, with independent testing results showing 99% less than 5 microns. Regardless of the delivery method, reduced particle size can result in increased therapeutic response — and a better product for your patients.

Features:

• Particle size – 100% <10 microns and 95–99% <5 microns
• Quality – Above and beyond USP standards
• Verified – Tested in PCCA formulations
• Consistent source – FDA-registered and GMP-compliant facilities

Estriol & Estradiol Dilutions

Estriol: PCCA #55-4893 | Estradiol: PCCA #55-4892

PCCA is the only company in the compounding industry that offers 10 mg/Gm dilutions of both micronised estriol (E3) and micronised estradiol (E2) in solution to meet the specialised needs of compounding pharmacists. Every batch of the dilution is meticulously tested to ensure accurate potency and content uniformity.

Each 1 Gm of PCCA Estriol Dilution contains 0.01 Gm (10 mg) of estriol, and each 1 Gm of PCCA Estradiol Dilution contains 0.01 Gm (10 mg) of estradiol in a 100% naturally derived, patent-pending solvent system. The loss on drying and potency assay have already been accounted for in the dilution to save time and help ensure accurate dosing. These dilutions can be used in making a wide variety of topical and vaginal hormone preparations².

Benefits:

• Safety – No free-flowing powders minimises exposure to highly potent hormones.
• Convenience – Eliminates the need to weigh static-prone powders and prepare various powder triturations for each formulation.
• Ease of use – Easily mixes into cream or gel base since the APIs are already solubilised, providing improved content uniformity.

Hormone therapy is designed specifically to your patient’s body.

HRT is most often prescribed to ease the symptoms of menopause, but it also can be used to treat a variety of conditions that women of all ages may experience, including:

• Pre-menstrual syndrome (PMS)
• Irregular menstrual cycle
• Moodiness
• Infertility
• Post-partum depression
• Weight gain
• Endometriosis
• Fibrocystic breasts
• Sleep disturbances
• Hot flashes
• Night sweats
• Decreased libido
• Painful sexual intercourse
• Vaginal dryness

Questions about PCCA Membership? Contact us today! 02 9316 1500